This book refutes the thesis of Samuel Huntington’s Clash of Civilizations. Instead, it supports the Alliance of Civilizations supervised by the United Nations. It describes religious-historical and cultural monuments in the region including Istanbul Cibali-Fener-Balat-Ayvansaray where three monotheistic religions live together under the peaceful conditions and they practice their religions. The thesis of Alliance of Civilizations has been examined theoretically within the context of the book. We hope that thesis of the Alliance of Civilizations, co-chaired by Prime Minister Recep Tayyip Erdogan and Spanish Prime Minister Zapatero under the umbrella of the United Nations, will make considerable contribution to the world peace